Purpose: The optimal macronutrient composition of the diet for the management of type 2 diabetes is debated, particularly with regard to the ideal proportion of fat and carbohydrates. The aim of the study was to explore the association of different proportions of fat and carbohydrates of the dietâwithin the ranges recommended by different guidelinesâwith metabolic risk factors. Methods: We studied 1785 people with type 2 diabetes, aged 50â75, enrolled in the TOSCA.IT Study. Dietary habits were assessed using a validated food-frequency questionnaire (EPIC). Anthropometry, fasting lipids, HbA1c and C-reactive protein (CRP) were measured. Results: Increasing fat intake from <25 to â¥35 % is associated with a significant increase in LDL-cholesterol, triglycerides, HbA1c and CRP (pÂ
Influence of dietary fat and carbohydrates proportions on plasma lipids, glucose control and low-grade inflammation in patients with type 2 diabetes. The TOSCA.IT Study / Vitale, M.; Masulli, M.; Rivellese, A. A.; Babini, A. C.; Boemi, M.; Bonora, E.; Buzzetti, R.; Ciano, O.; Cignarelli, M.; Cigolini, M.; Clemente, G.; Citro, G.; Corsi, L.; Dall'Aglio, E.; Del Prato, S.; Di Cianni, G.; Dolci, M. A.; Giordano, C.; Iannarelli, R.; Iovine, C.; Lapolla, A.; DI LAURO, Daniela; Leotta, S.; Mazzucchelli, C.; Montani, V.; Perriello, G.; Romano, Giacomo; Romeo, F.; Santarelli, L.; di Cola, R. Schiano; Squatrito, S.; Tonutti, L.; Trevisan, Riccardo; Turco, A. A.; Zamboni, C.; Riccardi, G.; Vaccaro, O.. - In: EUROPEAN JOURNAL OF NUTRITION. - ISSN 1436-6207. - 55:4(2016), pp. 1645-1651. [10.1007/s00394-015-0983-1]
Influence of dietary fat and carbohydrates proportions on plasma lipids, glucose control and low-grade inflammation in patients with type 2 diabetes. The TOSCA.IT Study
Dall'Aglio, E.;Vaccaro, O.
2016-01-01
Abstract
Purpose: The optimal macronutrient composition of the diet for the management of type 2 diabetes is debated, particularly with regard to the ideal proportion of fat and carbohydrates. The aim of the study was to explore the association of different proportions of fat and carbohydrates of the dietâwithin the ranges recommended by different guidelinesâwith metabolic risk factors. Methods: We studied 1785 people with type 2 diabetes, aged 50â75, enrolled in the TOSCA.IT Study. Dietary habits were assessed using a validated food-frequency questionnaire (EPIC). Anthropometry, fasting lipids, HbA1c and C-reactive protein (CRP) were measured. Results: Increasing fat intake from <25 to â¥35 % is associated with a significant increase in LDL-cholesterol, triglycerides, HbA1c and CRP (pÂI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
