Home-made micro-SPE cartridges using different adsorbent materials were tested for the desorption electrospray ionization-high resolution mass spectrometry (DESI-HRMS) determination of explosives like 2,4,6-trinitrotoluene, cyclotrimethylene-trinitramine, cyclotetramethylene-tetranitramine, pentaerythritol tetranitrate and trinitrophenylmethylnitramine in soil samples. Quantitation limits in the low nanogram per kilogram range proved reliability of the method for the detection of explosives at ultratrace-levels. The reduced sample preparation allowed for low costs and high-throughput analyses. Finally, the superior extraction capability of the method was proved obtaining DESI-HRMS responses at least five times higher than those achieved by performing DESI-HRMS analyses of solid-liquid extracts spotted onto commercial polytetrafluoroethylene slides
Micro solid-phase extraction coupled to desorption electrospray ionization-high resolution mass spectrometry for the analysis of explosives in soil / Bianchi, Federica; A., Gregori; G., Braun; C., Crescenzi; Careri, Maria. - In: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. - ISSN 1618-2642. - 407:(2015), pp. 931-938. [10.1007/s00216-014-8208-7]
Micro solid-phase extraction coupled to desorption electrospray ionization-high resolution mass spectrometry for the analysis of explosives in soil
BIANCHI, Federica
;CARERI, Maria
2015-01-01
Abstract
Home-made micro-SPE cartridges using different adsorbent materials were tested for the desorption electrospray ionization-high resolution mass spectrometry (DESI-HRMS) determination of explosives like 2,4,6-trinitrotoluene, cyclotrimethylene-trinitramine, cyclotetramethylene-tetranitramine, pentaerythritol tetranitrate and trinitrophenylmethylnitramine in soil samples. Quantitation limits in the low nanogram per kilogram range proved reliability of the method for the detection of explosives at ultratrace-levels. The reduced sample preparation allowed for low costs and high-throughput analyses. Finally, the superior extraction capability of the method was proved obtaining DESI-HRMS responses at least five times higher than those achieved by performing DESI-HRMS analyses of solid-liquid extracts spotted onto commercial polytetrafluoroethylene slidesI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
