Eighty systemic lupus erythematosus (SLE) patients attending 3 clinical centers were evaluated immunologically and immunogenetically. No HLA class II antigens were found to be significantly associated with SLE in these patients. A highly significant (P = 6.17 x 10(-7) association was observed between anticardiolipin antibodies and DR7. A lesser association (P less than 0.025) was also observed between DR2 and/or DR3 and anti-Ro (SS-A) antibodies. No relationship was found between any DR antigen and anti-Sm/RNP, anti-double-stranded DNA, or anti-La (SS-B) antibodies.
HLA-DR antigens and anticardiolipin antibodies in northern Italian systemic lupus erythematosus patients / Savi, Mario; Ferraccioli, Gf; Neri, Tauro Maria; Zanelli, P; Dall'Aglio, Pp; Tincani, A; Balestrieri, G; Carella, G; Cattaneo, R.. - In: ARTHRITIS AND RHEUMATISM. - ISSN 0004-3591. - 31:(1988), pp. 1568-1570.
HLA-DR antigens and anticardiolipin antibodies in northern Italian systemic lupus erythematosus patients.
SAVI, Mario;NERI, Tauro Maria;
1988-01-01
Abstract
Eighty systemic lupus erythematosus (SLE) patients attending 3 clinical centers were evaluated immunologically and immunogenetically. No HLA class II antigens were found to be significantly associated with SLE in these patients. A highly significant (P = 6.17 x 10(-7) association was observed between anticardiolipin antibodies and DR7. A lesser association (P less than 0.025) was also observed between DR2 and/or DR3 and anti-Ro (SS-A) antibodies. No relationship was found between any DR antigen and anti-Sm/RNP, anti-double-stranded DNA, or anti-La (SS-B) antibodies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
