Since the isolation in 1986 of HHV-6 from PBMCs of patient with AIDS and lymphoproliferative disorders, an effort has been made to understand the possible immunoplathogenitc role of this virus in human diseases. The presence and distribution of human herpesvirus 6 (HHV-6) variants was investigated by polymerase chain reaction in biopsy specimens of non-neoplastic lymph nodes form HIV-infected patients with lymphoadenopathy syndrome (LAS) and HIV-seronegative individuals. Diffusion of HHV-6 infection in lymph nodes and distribuzion of HHV-6 variants have been discussed.

Frequent detection of human herpesvirus 6 DNA in HIV-associated lymphadenopathy / Dolcetti, R.; DI LUCA, D.; Mirandola, Prisco; DE VITA, S.; DE RE, V.; Carbone, A.; Tirelli, U.; Cassai, E.; Boiocchi, M.. - In: THE LANCET. - ISSN 0140-6736. - 344:(1994), pp. 543-543.

Frequent detection of human herpesvirus 6 DNA in HIV-associated lymphadenopathy.

MIRANDOLA, Prisco;
1994-01-01

Abstract

Since the isolation in 1986 of HHV-6 from PBMCs of patient with AIDS and lymphoproliferative disorders, an effort has been made to understand the possible immunoplathogenitc role of this virus in human diseases. The presence and distribution of human herpesvirus 6 (HHV-6) variants was investigated by polymerase chain reaction in biopsy specimens of non-neoplastic lymph nodes form HIV-infected patients with lymphoadenopathy syndrome (LAS) and HIV-seronegative individuals. Diffusion of HHV-6 infection in lymph nodes and distribuzion of HHV-6 variants have been discussed.
1994
Frequent detection of human herpesvirus 6 DNA in HIV-associated lymphadenopathy / Dolcetti, R.; DI LUCA, D.; Mirandola, Prisco; DE VITA, S.; DE RE, V.; Carbone, A.; Tirelli, U.; Cassai, E.; Boiocchi, M.. - In: THE LANCET. - ISSN 0140-6736. - 344:(1994), pp. 543-543.
File in questo prodotto:
File Dimensione Formato  
066.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 1.28 MB
Formato Adobe PDF
1.28 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2429303
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 8
social impact