ABSTRACT Aim of the study was to evaluate the virulence, cell mediated immune response and histolesivity of three PRRSV strains, with ORF5 relevant genetic variations, isolated from either respiratory and reproductive field outbreaks. Changes in peripheral lymphocytes showed a cytotoxic natural response more evident than the acquired cytotoxic one. The results, in our experimental conditions, evidenced a different behaviour among the three PRRSV strains. Two of them, the 55/L/2000 and 162/L/2000, were less virulent than the 418/FL/2003 strain and of another PRSSV field strain (114/L/2000) previously investigated. The three PRRSV strains studied had moderate virulence, similar cell mediated immune response, but different histolesivity.

Study on the virulence, cell-mediated immune response and histolesivity of three field PRRSV strains with an ORF5 genetic variation / Corradi, Attilio; Ferrari, M.; Cantoni, Anna Maria; Robotti, C.; Alborali, L.; DI LECCE, Rosanna; Candotti, P.; Sandri, G. P.; Borghetti, Paolo. - In: VETERINARY RESEARCH COMMUNICATIONS. - ISSN 0165-7380. - 29:(2005), pp. 241-243. [10.1007/s11259-005-0052-y]

Study on the virulence, cell-mediated immune response and histolesivity of three field PRRSV strains with an ORF5 genetic variation

CORRADI, Attilio;CANTONI, Anna Maria;DI LECCE, Rosanna;BORGHETTI, Paolo
2005-01-01

Abstract

ABSTRACT Aim of the study was to evaluate the virulence, cell mediated immune response and histolesivity of three PRRSV strains, with ORF5 relevant genetic variations, isolated from either respiratory and reproductive field outbreaks. Changes in peripheral lymphocytes showed a cytotoxic natural response more evident than the acquired cytotoxic one. The results, in our experimental conditions, evidenced a different behaviour among the three PRRSV strains. Two of them, the 55/L/2000 and 162/L/2000, were less virulent than the 418/FL/2003 strain and of another PRSSV field strain (114/L/2000) previously investigated. The three PRRSV strains studied had moderate virulence, similar cell mediated immune response, but different histolesivity.
2005
Study on the virulence, cell-mediated immune response and histolesivity of three field PRRSV strains with an ORF5 genetic variation / Corradi, Attilio; Ferrari, M.; Cantoni, Anna Maria; Robotti, C.; Alborali, L.; DI LECCE, Rosanna; Candotti, P.; Sandri, G. P.; Borghetti, Paolo. - In: VETERINARY RESEARCH COMMUNICATIONS. - ISSN 0165-7380. - 29:(2005), pp. 241-243. [10.1007/s11259-005-0052-y]
File in questo prodotto:
File Dimensione Formato  
prrsv.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 88.89 kB
Formato Adobe PDF
88.89 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/1443941
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact