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NPM1 haploinsufficiency in MDS/AML with del(5q)/monosomy 5 1-gen-2007 R. L., Starza; Roti, Giovanni; L., Brandimarte; E., Varasano; F., Arcioni; A., Pierini; B., Crescenzi; D., Diverio; G., Guglielmini; M. F., Martelli; A., Aventin; C., Mecucci
Cryptic chromosome 9q34 deletion generates TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts in acute myeloid leukemia. 1-gen-2007 R., Rosati; R., La Starza; G., Barba; P., Gorello; V., Pierini; C., Matteucci; Roti, Giovanni; B., Crescenzi; T., Aloisi; Aversa, Franco; Martelli, M. F.; C., Mecucci
Chemical Genomic Screen Identifies Ionophores as Modulators of Notch1 in T-ALL 1-gen-2008 Roti, Giovanni; K. N., Ross; C., Mecucci; A. A., Ferrando; J. C., Aster; K., Stegmaier
Modulating Notch1 With Signature-based Small Molecule Library Screening 1-gen-2008 Roti, Giovanni; K., Ross; C., Mecucci; J., Aster; K., Stegmaier
Different genomic imbalances in low- and high-grade HCV-related lymphomas 1-gen-2008 Matteucci, C.; Bracci, M.; Barba, G.; Carbonari, M.; Casato, M.; Visentini, M.; Pulsoni, A.; Varasano, E.; Roti, Giovanni; La Starza, R.; Crescenzi, B.; Martelli, M. F.; Fiorilli, M.; Mecucci, C.
Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL 1-gen-2009 Roti, Giovanni; K. N., Ross; A. A., Ferrando; S. C., Blacklow; J., Aster; K., Stegmaier
Identification of AML1-ETO modulators by chemical genomics. 1-gen-2009 Roti, G; Corsello, Sm; Ross, Kn; Chow, Kt; Galinsky, I; Deangelo, Dj; Stone, Rm; Kung, Al; Golub, Tr; Stegmaier, K.
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. 1-gen-2010 Aste Amézaga, M; Zhang, N; Lineberger, Je; Arnold, Ba; Toner, Tj; Gu, M; Huang, L; Vitelli, S; Vo, Kt; Haytko, P; Zhao, Jz; Baleydier, F; L'Heureux, S; Wang, H; Gordon, Wr; Thoryk, E; Andrawes, Mb; Tiyanont, K; Stegmaier, K; Roti, Giovanni; Ross, Kn; Franlin, Ll; Wang, H; Wang, F; Chastain, M; Bett, Aj; Audoly, Lp; Aster, Jc; Blacklow, Sc; Huber, He
Targeting NOTCH1 in hematopoietic malignancy. 1-gen-2011 Roti, Giovanni; Stegmaier, K.
Intersecting High-Throughput Screens Identifies SERCA As a Target for Modulating NOTCH1 In Hematopoietic Malignancies 1-gen-2011 Roti, Giovanni; A., Carlton; K. N., Ross; M., Markstein; K., Pajcini; N., Perrimon; A. L., Kung; W. S., Pear; S. C., Blacklow; J. C., Aster; K., Stegmaier
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. 1-gen-2012 Banerji, V; Frumm, Sm; Ross, Kn; Li, Ls; Schinzel, Ac; Hahn, Ck; Kakoza, Rm; Chow, Kt; Ross, L; Alexe, G; Tolliday, N; Inguilizian, H; Galinsky, I; Stone, Rm; Deangelo, Dj; Roti, Giovanni; Aster, Jc; Hahn, Wc; Kung, Al; Stegmaier, K.
Genetic and proteomic approaches to identify cancer drug targets. 1-gen-2012 Roti, Giovanni; Stegmaier, K.
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. 1-gen-2013 Roti, Giovanni; Carlton, A; Ross, Kn; Markstein, M; Pajcini, K; Su, Ah; Perrimon, N; Pear, Ws; Kung, Al; Blacklow, Sc; Aster, Jc; Stegmaier, K.
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. 1-gen-2013 Frumm, Sm; Fan, Zp; Ross, Kn; Duvall, Jr; Gupta, S; Verplank, L; Suh, Bc; Holson, E; Wagner, Ff; Smith, Wb; Paranal, Rm; Bassil, Cf; Qi, J; Roti, Giovanni; Kung, Al; Bradner, Je; Tolliday, N; Stegmaier, K.
New Approaches to Target T-ALL 1-gen-2014 Roti, Giovanni; Kimberly, Stegmaier
WO/2016/073708 1-gen-2015 Bradner, James; Stegmaier, Kimberly; Qi, Jun; Varca, Anthony; Roti, Giovanni
Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E 1-gen-2017 Antonello, Zeus A.; Hsu, Nancy; Bhasin, Manoj; Roti, Giovanni; Joshi, Mukta; Hummelen, Paul Van; Ye, Emily; Lo, Agnes S.; Ananth Karumanchi, S.; Bryke, Christine R.; Nucera, Carmelo
Synergistic drug combinations with a CDK4/6 inhibitor in T-cell acute lymphoblastic leukemia 1-gen-2017 Pikman, Yana; Alexe, Gabriela; Roti, Giovanni; Conway, Amy Saur; Furman, Andrew; Lee, Emily S.; Place, Andrew E.; Kim, Sunkyu; Saran, Chitra; Modiste, Rebecca; Weinstock, David M.; Harris, Marian; Kung, Andrew L.; Silverman, Lewis B.; Stegmaier, Kimberly
Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling 1-gen-2018 Iniguez, Amanda Balboni; Alexe, Gabriela; Wang, Emily Jue; Roti, Giovanni; Patel, Sarvagna; Chen, Liying; Kitara, Samuel; Conway, Amy; Robichaud, Amanda L.; Stolte, Björn; Bandopadhayay, Pratiti; Goodale, Amy; Pantel, Sasha; Lee, Yenarae; Cheff, Dorian M.; Hall, Matthew D.; Guha, Rajarshi; Davis, Mindy I.; Menard, Marie; Nasholm, Nicole; Weiss, William A.; Qi, Jun; Beroukhim, Rameen; Piccioni, Federica; Johannessen, Cory; Stegmaier, Kimberly
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia 1-gen-2018 Baldoni, Stefano; Del Papa, Beatrice; Dorillo, Erica; Aureli, Patrizia; De Falco, Filomena; Rompietti, Chiara; Sorcini, Daniele; Varasano, Emanuela; Cecchini, Debora; Zei, Tiziana; Di Tommaso, Ambra; Rosati, Emanuela; Alexe, Gabriela; Roti, Giovanni; Stegmaier, Kimberly; Di Ianni, Mauro; Falzetti, Franca; Sportoletti, Paolo
Mostrati risultati da 41 a 60 di 96
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