Sfoglia per Autore
Predictive ability of regression models. Part II: Selection of the best predictive PLS model
1992-01-01 M., Baroni; S., Clementi; G., Cruciani; Costantino, Gabriele; D., Riganelli; E., Oberrauch
Predictive ability of regression models. Part I: Standard Deviation of Prediction Errors (SDEP)
1992-01-01 G., Cruciani; M., Baroni; S., Clementi; Costantino, Gabriele; D., Riganelli; B., Skagerberg
Predictive binding of .beta.-carboline inverse agonists and antagonists via the CoMFA/GOLPE approach
1992-01-01 M. S., Allen; A. J., Laloggia; L. J., Dorn; M. J., Martin; Costantino, Gabriele; T. J., Hagen; K. F., Koehler; P., Skolnick; J. M., Cook
Conformational requirements for interaction of L-Glutamic acid with metabotropic EEA receptors
1993-01-01 Costantino, Gabriele; B., Natalini; R., Pellicciari
Autocorrelation as a tool for a congruent description of molecules in 3D-QSAR studies
1993-01-01 S., Clementi; G., Cruciani; D., Riganelli; R., Valigi; Costantino, Gabriele; M., Baroni; S., Wold
Series Design
1993-01-01 S., Clementi; G., Cruciani; M., Baroni; Costantino, Gabriele
Comfa-derived Substituent Descriptors for Structure-Property Correlations
1993-01-01 H., Van der Waterbeemd; S., Clementi; Costantino, Gabriele; P. A., Carrupt; B., Testa
Generating optimal linear PLS estimation (GOLPE). An advanced chemometric tool for handling 3D-QSAR problems
1993-01-01 M., Baroni; Costantino, Gabriele; G., Cruciani; D., Riganelli; R., Valigi; S., Clementi
Definition of a Pharmacophore for the Metabotropic Glutamate Receptors Negatively Linked to Adenylyl Cyclase
1993-01-01 Costantino, Gabriele; B., Natalini; R., Pellicciari; F., Moroni; G., Lombardi
Heterocyclic modulators of the NMDA Receptor
1993-01-01 R., Pellicciari; B., Natalini; Costantino, Gabriele; A., Garzon; R., Luneia; M. R., Mahmoud; M., Marinozzi; M., Roberti; G. C., Rosato; S. A., Shiba
Disjoint Principal Properties of Organic Substituents
1994-01-01 H., Van der Waterbeemd; Costantino, Gabriele; S., Clementi; G., Cruciani; R., Valigi
Modulation of the Kynurenine Pathway in Search for New Neuroprotective Agents. Synthesis and Preliminary Evaluation of (m-Nitrobenzoyl)alanine, a Potent Inhibitor of Kynurenine-3-hydroxylase
1994-01-01 R., Pellicciari; B., Natalini; Costantino, Gabriele; M. R., Mamhoud; L., Mattoli; B., Sadeghpour; F., Moroni; A., Chiarugi; F., Carpenedo
The pseudoactive site as a tool for indirect drug design. Application to inhibitors of kynurenine-3-hydroxylase
1995-01-01 Costantino, Gabriele; B., Natalini; L., Mattoli; R., Pellicciari
1-Aminoindane-1,5-dicarboxylic Acid: a Novel Antagonist at Phospholipase C Linked Metabotropic Glutamate Receptors
1995-01-01 R., Pellicciari; R., Luneia; Costantino, Gabriele; M., Marinozzi; B., Natalini; P., Jackobsen; A., Kanstrup; G., Lombardi; F., Moroni; C., Thomsen
Synthesis and Biological Evaluation of 6-Carboxy-3,4-methanoprolines, New Rigid Glutamate Analogs
1995-01-01 M., Marinozzi; B., Natalini; C., Thomsen; M. H., Ni; Costantino, Gabriele; R., Pellicciari
Synthesis and Pharmcological Characterization of All Sixteen Stereoisomers of 2-(2'-Carboxy-3'-phenylcyclopropyl)glycine. Focus on (2S,1'S,2'S,3'R)-2-(2'Carboxy-3'-phenylcyclopropyl)glycine, a Novel and Selective Group II Metabotropic Glutamate Receptors Antagonist
1996-01-01 R., Pellicciari; M., Marinozzi; B., Natalini; Costantino, Gabriele; R., Luneia; G., Giorgi; F., Moroni; C., Thomsen
Kynurenine-3-hydroxylase and its Selective Inhibitors: Molecular Modelling Studies
1996-01-01 Costantino, Gabriele; L., Mattoli; B., Natalini; F., Moroni; R., Pellicciari
S-(+)-2-(3'-Carboxy-bicyclo[1.1.1]pentyl)glycine, a Structurally New Group I Metabotropic Glutamate Receptor Antagonist
1996-01-01 R., Pellicciari; M., Raimondo; M., Marinozzi; B., Natalini; Costantino, Gabriele; C., Thomsen
Asymmetric Synthesis of Enantiomerically Pure (2S,1'S,2'S,3'R)-phenylcarboxycyclopropylglycine (PCCG-4): A Potent and Selective Ligand at Group II Metabotropic Glutamate Receptors
1996-01-01 M., Marinozzi; B., Natalini; Costantino, Gabriele; P., Tijskens; C., Thomsen; R., Pellicciari
Homology Modeling of Metabotropic Glutamate Receptors (mGluRs). Structural Motifs Affecting Binding Modes and Pharmacological Profile of mGluR1 Agonists and Competitive Antagonists
1996-01-01 Costantino, Gabriele; R., Pellicciari
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