Sfoglia per Autore
Arsenic Trioxide (ATO) Interacts Synergistically with MEK Inhibitors to Induce Apoptosis in STI571-Resistant Bcr-Abl Mutants
2009-01-01 Lunghi, P; Mazzera, L; Corradi, A; Cantoni, Am; Jottini, S; Lombardi, G; Ricca, M; Arienti, D; Rizzoli, V; Deininger, Mwn; Bonati, A
The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting
2009-01-01 Lunghi, P.; Costanzo, A.; Mazzera, L.; Rizzoli, V.; Levrero, M.; Bonati, A.
MDM2 inhibition synergistically enhances cytotoxicity of MEK1 inhibitor and arsenic trioxide (ATO) in AML blasts that retain a functional P53 pathway
2008-01-01 Mazzera, L; Lunghi, P; Mangoni, M; Caramatti, Cecilia; Rizzoli, V; Bonati, A.
Hypoxia and Hypoxia Inducible Factor (HIF)-1α in Multiple Myeloma: Effect on the Pro-Angiogenic Signature of Myeloma Cells and the Bone Marrow Microenvironment.
2008-01-01 Colla, S.; Storti, P.; Donofrio, Gaetano; Lazzaretti, M.; Bonomini, S.; Lunghi, P.; Crugnola, M.; Bolzoni, M.; Galla, L.; Lippolito, ; Martella, E.; Sammarelli, G.; Craviotto, L.; Caramatti, Cecilia; Mangoni, M.; Bonati, A.; Giuliani, V. RIZZOLI AND N.
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia
2008-01-01 Steelman, Ls; Abrams, Sl; Whelan, J; Bertrand, Fe; Ludwig, De; Bäsecke, J; Libra, M; Stivala, F; Milella, M; Tafuri, A; Lunghi, P; Bonati, Antonio; Martelli, Am; Mccubrey, Ja
THE COMBINATION OF MEK INHIBITORS AND ARSENIC TRIOXIDE TRIGGERS IN VITRO AND IN VIVO SYNERGISTIC CYTOTOXICITY IN MULTIPLE MYELOMA THROUGH MULTIPLE SIGNALING PATHWAYS
2008-01-01 Lunghi, P; Mazzera, L; Lombardi, G; Ricca, M; Corradi, A; Cantoni, Am; Giuliani, N; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, V; Bonati, A
Combined treatment with the MEK inhibitor PD0325901 and Arsenic Trioxide has potent anti-tumor activity in vivo against human multiple myeloma xenograft model.
2008-01-01 Lunghi, P; Mazzera, L; Lombardi, G; Ricca, M; Corradi, Attilio; Cantoni, Anna Maria; Giuliani, Nicola; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, Vittorio; Bonati, Antonio
Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors.
2008-01-01 Mccubrey, Ja; Milella, M; Tafuri, A; Martelli, Am; Lunghi, Paolo; Bonati, Antonio; Cervello, M; Lee, Jt; Steelman, Ls
Combined Treatment with the Mek Inhibitor PD0325901 and Arsenic Trioxide Has Potent Antitumor Activity in Vivo against Human Multiple Myeloma Xenograft Model
2008-01-01 Lunghi, P; Mazzera, L; Lombardi, G; Ricca, M; Corradi, A; Cantoni, Am; Giuliani, N; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, V; Bonati, A
MDM2 inhibition synergistically enhances cytotoxicity of MEK1 inhibitor and Arsenic Trioxide (ATO) in AML blasts that retain a functional p53 pathway
2008-01-01 Mazzera, L; Lunghi, P; Mangoni, Marcellina; Caramatti, C; Rizzoli, V; Bonati, Antonio
The combination of MEK inhibitors and Arsenic Trioxide triggers in vitro and in vivo synergistic cytotoxicity in multiple myeloma through multiple signaling pathways
2008-01-01 Lunghi, P; Mazzera, L; Lombardi, G; Ricca, M; Corradi, Attilio; Cantoni, Anna Maria; Giuliani, Nicola; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, Vittorio; Bonati, Antonio
Hypoxia and Hypoxia Inducible Factor (HIF)-1{alpha} in Multiple Myeloma: Effect on the Pro-Angiogenic Signature of Myeloma Cells and the Bone Marrow Microenvironment
2008-01-01 Colla, S; Storti, Paola; Donofrio, Gaetano; Lazzaretti, Mirca; Bonomini, S; Lunghi, Paolo; Crugnola, M; Bolzoni, Marina; Galla, L; Ippolito, L; Martella, E; Sammarelli, Gabriella; Craviotto, Luisa; Caramatti, Cecilia; Mangoni, Marcellina; Bonati, A; Rizzoli, Vittorio; Giuliani, Nicola
Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.
2008-01-01 Mccubrey, Ja; Steelman, Ls; Abrams, Sl; Bertrand, Fe; Ludwig, De; Bäsecke, J; Libra, M; Stivala, F; Milella, M; Tafuri, A; Lunghi, P; Bonati, Antonio; Martelli, Am
Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy
2008-01-01 Mccubrey, J. A.; Steelman, L. S.; Abrams, S. L.; Bertrand, F. E.; Ludwig, D. E.; Basecke, J.; Libra, M.; Stivala, F.; Milella, M.; Tafuri, A.; Lunghi, P.; Bonati, A.; Martelli, A. M.
Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways
2008-01-01 Lunghi, Paolo; Giuliani, Nicola; Mazzera, L; Lombardi, G; Ricca, M; Corradi, Attilio; Cantoni, Anna Maria; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, Vittorio; Bonati, Antonio
p73 and p53 pathway in human breast cancers.
2007-01-01 Bozzetti, C; Nizzoli, R; Musolino, A; Martella, Em; Crafa, Pellegrino; Lagrasta, Costanza Anna Maria; Camisa, R; Bonati, Antonio; Lunghi, P; Ardizzoni, A.
The new tumor suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of pro-angiogenic molecules by myeloma cells and suppresses hypoxia inducible factor (HIF)-1{alpha} activity being involved in myeloma-induced angiogenesis.
2007-01-01 Colla, S; Tagliaferri, Sara; Morandi, F; Lunghi, Paolo; Donofrio, Gaetano; Martorana, D; Mancini, C; Lazzaretti, Mirca; Mazzera, L; Ravanetti, L; Bonomini, S; Ferrari, L; Miranda, C; Ladetto, M; Neri, Tauro Maria; Neri, A; Greco, A; Mangoni, Marcellina; Bonati, Antonio; Rizzoli, Vittorio; Giuliani, Nicola
p73 and p53 pathway in human breast cancers [9]
2007-01-01 Bozzetti, C.; Nizzoli, R.; Musolino, A.; Martella, E. M.; Crafa, P.; Lagrasta, C. A.; Camisa, R.; Bonati, A.; Lunghi, P.; Ardizzoni, A.
MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis
2006-01-01 Lunghi, P.; Costanzo, A.; Salvatore, L.; Noguera, N.; Mazzera, L.; Tabilio, A.; Lo-Coco, F.; Levrero, M.; Bonati, A.
Role of GSTP1-1 in mediating the effect of As2O3 in the Acute Promyelocytic Leukemia cell line NB4
2006-01-01 Bernardini, S.; Nuccetelli, M.; Noguera, N. I.; Bellincampi, L.; Lunghi, P.; Bonati, A.; Mann, K.; Miller, Jr. W. H.; Federici, G.; Lo Coco, F.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Arsenic Trioxide (ATO) Interacts Synergistically with MEK Inhibitors to Induce Apoptosis in STI571-Resistant Bcr-Abl Mutants | 1-gen-2009 | Lunghi, P; Mazzera, L; Corradi, A; Cantoni, Am; Jottini, S; Lombardi, G; Ricca, M; Arienti, D; Rizzoli, V; Deininger, Mwn; Bonati, A | |
| The p53 family protein p73 provides new insights into cancer chemosensitivity and targeting | 1-gen-2009 | Lunghi, P.; Costanzo, A.; Mazzera, L.; Rizzoli, V.; Levrero, M.; Bonati, A. | |
| MDM2 inhibition synergistically enhances cytotoxicity of MEK1 inhibitor and arsenic trioxide (ATO) in AML blasts that retain a functional P53 pathway | 1-gen-2008 | Mazzera, L; Lunghi, P; Mangoni, M; Caramatti, Cecilia; Rizzoli, V; Bonati, A. | |
| Hypoxia and Hypoxia Inducible Factor (HIF)-1α in Multiple Myeloma: Effect on the Pro-Angiogenic Signature of Myeloma Cells and the Bone Marrow Microenvironment. | 1-gen-2008 | Colla, S.; Storti, P.; Donofrio, Gaetano; Lazzaretti, M.; Bonomini, S.; Lunghi, P.; Crugnola, M.; Bolzoni, M.; Galla, L.; Lippolito, ; Martella, E.; Sammarelli, G.; Craviotto, L.; Caramatti, Cecilia; Mangoni, M.; Bonati, A.; Giuliani, V. RIZZOLI AND N. | |
| Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia | 1-gen-2008 | Steelman, Ls; Abrams, Sl; Whelan, J; Bertrand, Fe; Ludwig, De; Bäsecke, J; Libra, M; Stivala, F; Milella, M; Tafuri, A; Lunghi, P; Bonati, Antonio; Martelli, Am; Mccubrey, Ja | |
| THE COMBINATION OF MEK INHIBITORS AND ARSENIC TRIOXIDE TRIGGERS IN VITRO AND IN VIVO SYNERGISTIC CYTOTOXICITY IN MULTIPLE MYELOMA THROUGH MULTIPLE SIGNALING PATHWAYS | 1-gen-2008 | Lunghi, P; Mazzera, L; Lombardi, G; Ricca, M; Corradi, A; Cantoni, Am; Giuliani, N; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, V; Bonati, A | |
| Combined treatment with the MEK inhibitor PD0325901 and Arsenic Trioxide has potent anti-tumor activity in vivo against human multiple myeloma xenograft model. | 1-gen-2008 | Lunghi, P; Mazzera, L; Lombardi, G; Ricca, M; Corradi, Attilio; Cantoni, Anna Maria; Giuliani, Nicola; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, Vittorio; Bonati, Antonio | |
| Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors. | 1-gen-2008 | Mccubrey, Ja; Milella, M; Tafuri, A; Martelli, Am; Lunghi, Paolo; Bonati, Antonio; Cervello, M; Lee, Jt; Steelman, Ls | |
| Combined Treatment with the Mek Inhibitor PD0325901 and Arsenic Trioxide Has Potent Antitumor Activity in Vivo against Human Multiple Myeloma Xenograft Model | 1-gen-2008 | Lunghi, P; Mazzera, L; Lombardi, G; Ricca, M; Corradi, A; Cantoni, Am; Giuliani, N; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, V; Bonati, A | |
| MDM2 inhibition synergistically enhances cytotoxicity of MEK1 inhibitor and Arsenic Trioxide (ATO) in AML blasts that retain a functional p53 pathway | 1-gen-2008 | Mazzera, L; Lunghi, P; Mangoni, Marcellina; Caramatti, C; Rizzoli, V; Bonati, Antonio | |
| The combination of MEK inhibitors and Arsenic Trioxide triggers in vitro and in vivo synergistic cytotoxicity in multiple myeloma through multiple signaling pathways | 1-gen-2008 | Lunghi, P; Mazzera, L; Lombardi, G; Ricca, M; Corradi, Attilio; Cantoni, Anna Maria; Giuliani, Nicola; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, Vittorio; Bonati, Antonio | |
| Hypoxia and Hypoxia Inducible Factor (HIF)-1{alpha} in Multiple Myeloma: Effect on the Pro-Angiogenic Signature of Myeloma Cells and the Bone Marrow Microenvironment | 1-gen-2008 | Colla, S; Storti, Paola; Donofrio, Gaetano; Lazzaretti, Mirca; Bonomini, S; Lunghi, Paolo; Crugnola, M; Bolzoni, Marina; Galla, L; Ippolito, L; Martella, E; Sammarelli, Gabriella; Craviotto, Luisa; Caramatti, Cecilia; Mangoni, Marcellina; Bonati, A; Rizzoli, Vittorio; Giuliani, Nicola | |
| Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. | 1-gen-2008 | Mccubrey, Ja; Steelman, Ls; Abrams, Sl; Bertrand, Fe; Ludwig, De; Bäsecke, J; Libra, M; Stivala, F; Milella, M; Tafuri, A; Lunghi, P; Bonati, Antonio; Martelli, Am | |
| Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy | 1-gen-2008 | Mccubrey, J. A.; Steelman, L. S.; Abrams, S. L.; Bertrand, F. E.; Ludwig, D. E.; Basecke, J.; Libra, M.; Stivala, F.; Milella, M.; Tafuri, A.; Lunghi, P.; Bonati, A.; Martelli, A. M. | |
| Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways | 1-gen-2008 | Lunghi, Paolo; Giuliani, Nicola; Mazzera, L; Lombardi, G; Ricca, M; Corradi, Attilio; Cantoni, Anna Maria; Salvatore, L; Riccioni, R; Costanzo, A; Testa, U; Levrero, M; Rizzoli, Vittorio; Bonati, Antonio | |
| p73 and p53 pathway in human breast cancers. | 1-gen-2007 | Bozzetti, C; Nizzoli, R; Musolino, A; Martella, Em; Crafa, Pellegrino; Lagrasta, Costanza Anna Maria; Camisa, R; Bonati, Antonio; Lunghi, P; Ardizzoni, A. | |
| The new tumor suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of pro-angiogenic molecules by myeloma cells and suppresses hypoxia inducible factor (HIF)-1{alpha} activity being involved in myeloma-induced angiogenesis. | 1-gen-2007 | Colla, S; Tagliaferri, Sara; Morandi, F; Lunghi, Paolo; Donofrio, Gaetano; Martorana, D; Mancini, C; Lazzaretti, Mirca; Mazzera, L; Ravanetti, L; Bonomini, S; Ferrari, L; Miranda, C; Ladetto, M; Neri, Tauro Maria; Neri, A; Greco, A; Mangoni, Marcellina; Bonati, Antonio; Rizzoli, Vittorio; Giuliani, Nicola | |
| p73 and p53 pathway in human breast cancers [9] | 1-gen-2007 | Bozzetti, C.; Nizzoli, R.; Musolino, A.; Martella, E. M.; Crafa, P.; Lagrasta, C. A.; Camisa, R.; Bonati, A.; Lunghi, P.; Ardizzoni, A. | |
| MEK1 inhibition sensitizes primary acute myelogenous leukemia to arsenic trioxide-induced apoptosis | 1-gen-2006 | Lunghi, P.; Costanzo, A.; Salvatore, L.; Noguera, N.; Mazzera, L.; Tabilio, A.; Lo-Coco, F.; Levrero, M.; Bonati, A. | |
| Role of GSTP1-1 in mediating the effect of As2O3 in the Acute Promyelocytic Leukemia cell line NB4 | 1-gen-2006 | Bernardini, S.; Nuccetelli, M.; Noguera, N. I.; Bellincampi, L.; Lunghi, P.; Bonati, A.; Mann, K.; Miller, Jr. W. H.; Federici, G.; Lo Coco, F. |
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